Research Assistant I, Simmons Cancer Center Why UT Southwestern? With over 75 years of excellence in Dallas-Fort Worth, Texas, UT Southwestern is committed to excellence, innovation, teamwork, and compassion. As a world‑renowned medical and research center, we strive to provide the best possible care, resources, and benefits for our valued employees. Ranked as the number 1 hospital in Dallas‑Fort Worth according to U.S. News & World Report, we invest in you with opportunities for career growth and development to align with your future goals. Our highly competitive benefits package offers healthcare, PTO and paid holidays, on‑site childcare, wage, merit increases and so much more. We invite you to be a part of the UT Southwestern team where you’ll discover a culture of teamwork, professionalism, and a rewarding career! Job Summary Works under general direction to provide responsible and skilled technical assistance in performing assignments requiring experience and good knowledge of techniques and practices related to particular field of medical and scientific research. Candidate will perform more difficult scientific and medical research work in the science area such as biology, chemistry, physics, or other related scientific fields. Synthesize and characterize PEG‑, PCL‑, and other related polymer‑based drug conjugates. Optimize linker chemistry, drug conjugation strategies, and loading efficiencies. Perform cell culture experiments with immune cells, cancer cell lines, and primary cells; access cytotoxicity, cellular uptake, trafficking, and immune activation. Assist with animal studies, including in vivo dosing, tissue processing, immunohistochemistry, and fluorescence imaging. Maintain lab inventory, prepare buffers and reagents, ensure protocol compliance, and keep accurate, detailed laboratory notebooks; assist with data processing and analysis. Candidate will work under general direction to provide responsible, skilled technical assistance in developing polymer‑drug chimeras (PDCs) for immune engineering and cancer therapy. Responsibilities Performs more difficult scientific and medical research work in science area such as biology, chemistry, physics, or other related scientific field. Constructs, assembles, and operates laboratory equipment and apparatus. Records and evaluates data obtained from work assignments for use in scientific papers. Collaborates with supervisor or other research personnel in preparation of scientific papers for publication. Reads literature and confers with supervisor concerning procedures and implementation. Collects and organizes research data for project reports. May plan for, and provide working supervision to, work of Research Technicians or other laboratory personnel of lower grade. Performs other duties as assigned. Qualifications Education: Master's Degree with major coursework in field of assignment and no experience required or Bachelor's Degree with major coursework in field of assignment or Completion of 2 years of college with emphasis in coursework in field of assignment or High School Diploma or GED equivalent. Experience: 1 year Research experience at level of Research Technician or equivalent with Bachelor's degree or 4 years Research experience including two years at level of Research Technician or equivalent with 2 years of college or 6 years Research experience with High School Diploma or GED equivalent including 2 years at level of Research Technician or equivalent. Benefits PPO medical plan, available day one at no cost for full‑time employee‑only coverage. 100% coverage for preventive healthcare‑no copay. Paid Time Off, available day one. Retirement Programs through the Teacher Retirement System of Texas (TRS). Paid Parental Leave Benefit. Wellness programs. Tuition Reimbursement. Public Service Loan Forgiveness (PSLF) Qualified Employer. Learn more about these and other UTSW employee benefits! Security and EEO Statement Security This position is security‑sensitive and subject to Texas Education Code 51.215, which authorizes UT Southwestern to obtain criminal history record information. EEO UT Southwestern Medical Center is committed to an educational and working environment that provides equal opportunity to all members of the University community. As an equal opportunity employer, UT Southwestern prohibits unlawful discrimination, including discrimination on the basis of race, color, religion, national origin, sex, sexual orientation, gender identity, gender expression, age, disability, genetic information, citizenship status, or veteran status. Primary Location Texas-Dallas-5323 Harry Hines Blvd Work Locations 5323 Harry Hines Blvd Job Research & Laboratory Organization 371004 - SCC‑Lab Gao Schedule Full‑time Shift Day Job Employee Status Regular Job Type Standard Job Posting Dec 2, 2025, 3:23:58 AM Seniority level Not Applicable Employment type Full‑time Job function Research, Analyst, and Information Technology Hospitals and Health Care #J-18808-Ljbffr UT Southwestern Medical Center
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